학술논문
Clinicopathological Pattern and Management of Primary Lung Cancer in Ilorin, Nigeria.
Document Type
Academic Journal
Author
Adeoye PO; Division of Thoracic & Cardiovascular Surgery, Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Desalu OO; Division of Respiratory Medicine, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Ofoegbu CKP; Department of Pathology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Fawibe AE; Division of Respiratory Medicine, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Salami AK; Division of Respiratory Medicine, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Akanbi OR; Division of Thoracic & Cardiovascular Surgery, Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Opeyemi CM; Division of Respiratory Medicine, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Ibrahim OOK; Department of Pathology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Ojuawo OB; Division of Respiratory Medicine, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Aladesanmi AO; Division of Respiratory Medicine, Department of Medicine, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.; Olaoye I; Division of Thoracic & Cardiovascular Surgery, Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.
Source
Publisher: West African College Of Physicians And West African College Of Surgeons Country of Publication: Nigeria NLM ID: 8301891 Publication Model: Print Cited Medium: Print ISSN: 0189-160X (Print) Linking ISSN: 0189160X NLM ISO Abbreviation: West Afr J Med Subsets: MEDLINE
Subject
Language
English
ISSN
0189-160X
Abstract
Background: Lung cancer incidence and mortality rates have increased in some low and medium-resourced countries.
Objectives: This study aimed to describe the clinicopathological pattern and management of lung cancer seen in our setting.
Methods: We reviewed cases of pulmonary neoplasm diagnosed and managed at the University of Ilorin teaching hospital over eight years. Cases with tissue diagnosis were enrolled in the study and relevant clinical data were collected from the medical record using a proforma.
Design: Hospital-based retrospective study.
Results: Out of the 71 cases of primary lung cancer reviewed, 44(62%) were males and the male to female ratio was 2:1. The mean age was 62±14 years and the occurrence was highest in aged 50-69 years. Thirty (42.3%) with histories of tobacco smoking were males. Adenocarcinoma accounted for 34(54.9%), 23(32.4%) were squamous cell carcinoma, 2(2.8%) were large cell carcinoma and 6(8.5%) were other histological variants. The majority (82.7%) presented at stage III-IV lung cancers, 56.3% had malignant pleural effusion and 74.6% received palliative care. Thirty-eight (53.3%) had chest tube drainage, 19(26.7%) underwent chemical pleurodesis and 22(31.0%) received Cisplatin-based systemic chemotherapy. One patient had curative surgery and none received radiotherapy. At 12 months, 4 (5.6%) were still alive, 14(19.7%) cases had medical records of their death and 53(74.7%) were lost to follow up.
Conclusion: This study has highlighted the clinicopathological trend, high rate of mortality and late presentation of lung cancer in our setting. There is a need to increase the awareness of the warning signs and risk factors to ensure early detection and facilitate curative therapy.
Competing Interests: The author certifies that there is no conflict of interest in connection with the submitted article. All Conflict of Interest Forms are on file with the journal publication and are available on request.
(Copyright © 2021 by West African Journal of Medicine.)
Objectives: This study aimed to describe the clinicopathological pattern and management of lung cancer seen in our setting.
Methods: We reviewed cases of pulmonary neoplasm diagnosed and managed at the University of Ilorin teaching hospital over eight years. Cases with tissue diagnosis were enrolled in the study and relevant clinical data were collected from the medical record using a proforma.
Design: Hospital-based retrospective study.
Results: Out of the 71 cases of primary lung cancer reviewed, 44(62%) were males and the male to female ratio was 2:1. The mean age was 62±14 years and the occurrence was highest in aged 50-69 years. Thirty (42.3%) with histories of tobacco smoking were males. Adenocarcinoma accounted for 34(54.9%), 23(32.4%) were squamous cell carcinoma, 2(2.8%) were large cell carcinoma and 6(8.5%) were other histological variants. The majority (82.7%) presented at stage III-IV lung cancers, 56.3% had malignant pleural effusion and 74.6% received palliative care. Thirty-eight (53.3%) had chest tube drainage, 19(26.7%) underwent chemical pleurodesis and 22(31.0%) received Cisplatin-based systemic chemotherapy. One patient had curative surgery and none received radiotherapy. At 12 months, 4 (5.6%) were still alive, 14(19.7%) cases had medical records of their death and 53(74.7%) were lost to follow up.
Conclusion: This study has highlighted the clinicopathological trend, high rate of mortality and late presentation of lung cancer in our setting. There is a need to increase the awareness of the warning signs and risk factors to ensure early detection and facilitate curative therapy.
Competing Interests: The author certifies that there is no conflict of interest in connection with the submitted article. All Conflict of Interest Forms are on file with the journal publication and are available on request.
(Copyright © 2021 by West African Journal of Medicine.)