학술논문
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.
Document Type
Journal Article
Author
Bowtell, David D.; Böhm, Steffen; Ahmed, Ahmed A.; Aspuria, Paul-Joseph; Bast, Robert C.; Beral, Valerie; Berek, Jonathan S.; Birrer, Michael J.; Blagden, Sarah; Bookman, Michael A.; Brenton, James D.; Chiappinelli, Katherine B.; Martins, Filipe Correia; Coukos, George; Drapkin, Ronny; Edmondson, Richard; Fotopoulou, Christina; Gabra, Hani; Galon, Jérôme; Gourley, Charlie
Source
Subject
*CANCER-related mortality
*HEALTH outcome assessment
*CANCER research
*MISSENSE mutation
*CELL cycle
*OVARIAN tumors
*PROGNOSIS
*SURVIVAL
*TUMORS
*TUMOR grading
*PREVENTION
OVARIAN cancer patients
TUMOR prevention
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Language
ISSN
1474-175X
Abstract
High-grade serous ovarian cancer (HGSOC) accounts for 70-80% of ovarian cancer deaths, and overall survival has not changed significantly for several decades. In this Opinion article, we outline a set of research priorities that we believe will reduce incidence and improve outcomes for women with this disease. This 'roadmap' for HGSOC was determined after extensive discussions at an Ovarian Cancer Action meeting in January 2015. [ABSTRACT FROM AUTHOR]