학술논문

Measuring Activated Clotting Time during Cardiac Catheterization and PCI: The Effect of the Sampling Site.
Document Type
Journal Article
Source
Journal of Interventional Cardiology. 9/13/2021, p1-6. 6p.
Subject
*CARDIAC catheterization
*ARTERIAL catheters
*CARDIAC surgery
*STANDARD deviations
*STATISTICAL significance
*BLOOD sampling
Language
ISSN
0896-4327
Abstract
Results: In 100 patients (mean age 67.1, 65% male), no significant differences were observed in ACT values obtained from the guiding catheter and arterial sheath (mean difference (MD) -18.3 s; standard deviation (SD) 96 s; P=0.067). Contrarily, ACT values obtained from the intravenous line were significantly lower as compared to values obtained from the guiding catheter (MD 25.7 s; SD 75.5; P=0.003) and arterial sheath (MD 39 s; SD 102.8; P < 0.001). Furthermore, ACT measurements from the arterial sheath showed a statistically significant proportional bias when compared to the other sampling sites (sheath vs. catheter, r = 0.761, P=0.001; sheath vs. IVL, r = 1.013, P < 0.001).Conclusions: The present study shows statistical significance and possibly clinically relevant variations between ACT measurements from different sample sites. Bias in ACT measurements may be minimized by using uniform protocols for ACT measurement during cardiac catheterization. [ABSTRACT FROM AUTHOR]