학술논문
Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.
Document Type
Article
Author
Source
Subject
*MUTAGENESIS
*NUCLEOTIDE sequence
*DATABASES
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*
Language
ISSN
0028-0836
Abstract
Presents research which described a high-throughput mutagenesis method based on gene trapping that allows the automated identification of sequence tags from mutated genes. Use of expressed sequence tags (ESTs) in gene sequencing; Impact of ability to create mutations in embryonic stem (ES) cells; Benefits of method; Use for study of gene function on a large scale; Library of ES cells called Omnibank.