학술논문

Nanocomposites based on poly(glycerol sebacate) with silica nanoparticles with potential application in dental tissue engineering.
Document Type
Article
Source
International Journal of Polymeric Materials & Polymeric Biomaterials. 2020, Vol. 69 Issue 12, p761-772. 12p.
Subject
*NANOCOMPOSITE materials
*TISSUE engineering
*GLYCERIN
*NANOPARTICLES
*SILICONES
*SILICA nanoparticles
Language
ISSN
0091-4037
Abstract
Nanocomposites based on poly(glycerol sebacate) with silica nanoparticles were synthesized to explore their potential use in the biomedical field. The nanoparticles were two distinct polyhedral oligomeric silsesquioxanes (POSS), both used at 5% wt/wt concentration, specifically methacrylisobutyl POSS and methacryl POSS. These materials were investigated for their possible application as coatings as well as with regenerative purposes in dental engineering, and their viability for this application was assessed. Thus, pure PGS and nanohybrids thereof were obtained as scaffolds (that is, porous structures, designed with regenerative purposes) and as films (intended for coatings and to be used as controls). [ABSTRACT FROM AUTHOR]