학술논문

Non-alcoholic fatty liver disease and obesity: the role of the gut bacteria.
Document Type
Article
Source
European Journal of Nutrition. Aug2019, Vol. 58 Issue 5, p1771-1784. 14p. 4 Charts.
Subject
*METABOLIC syndrome risk factors
*OBESITY complications
*DIET
*DIETARY supplements
*EXERCISE therapy
*FATTY liver
*INFLAMMATION
*INGESTION
*GUT microbiome
*FECAL microbiota transplantation
*DISEASE risk factors
Language
ISSN
1436-6207
Abstract
Non-alcoholic fatty-liver disease (NAFLD) is now considered one of the leading causes of liver disease worldwide and is associated with metabolic syndrome and obesity. There are several factors contributing to the disease state. Recent research suggests that the intestinal microbiota (IM) and bacterial products may play a role through several mechanisms which include increased energy uptake, intestinal permeability and chronic inflammation. In addition to diet and exercise, treatment options targeting the IM are being investigated and include the use of pre-, pro- and synbiotics as well as the possibility of fecal microbial transfers. This literature review explores the relationship between NAFLD and the IM as well as highlight new IM treatment options that may become available in the near future. [ABSTRACT FROM AUTHOR]