부산대학교 도서관

Introduction Besides the target joints (elbow, knee and ankle), the hip is one of the commonly affected joints in haemophilic arthropathy . Hip arthroplasty is the therapy of choice after failure of conservative treatment. There are only limited data on long-term results after primary total hip arthroplasty ( THA). Aim The aim of this retrospective study was to analyse clinical outcome and complication rate after total hip replacement in patients with severe haemophilic arthropathy . Methods Forty-three patients with haemophilia ( PWH), one patient with von Willebrand disease and one patient with a Factor- VII-deficiency undergoing 49 total hip arthroplasties, were evaluated in a retrospective study . Harris hip score ( HHS), range of motion ( ROM), pain status (visual analogue scale, VAS) complication rate and patient satisfaction were assessed at a mean follow-up of 11.5 years (range: 3-32). Results HSS, ROM and VAS improved significantly combined with high patient satisfaction. In total, three (6.1%) periprosthetic infections and five (10.2%) aseptic implant loosenings occurred after THA leading to revision arthroplasty. In two (4.1%) cases, a pseudotumour and one (2.0%) periarticular ossification had to be resected after THA . Conclusion Total hip replacement in PWH leads to a significant increase of function, reduction of pain and a high satisfaction. Due to the relatively high complication rate (infections and aseptic loosening) compared to patients without haemophilia, an individual assessment of the risk-benefit ratio from surgical and haemostaseological point of view is needed. [ABSTRACT FROM AUTHOR]