학술논문

Kidney transplantation in HIV-positive patients: a report of 14 cases.
Document Type
Article
Source
Journal of the International AIDS Society. Nov2012 Supplement S4, Vol. 15, pn/a-n/a. 2p. 1 Chart, 1 Graph.
Subject
*HIV-positive persons
*KIDNEY transplantation
*HIGHLY active antiretroviral therapy
*HIV
*DRUG monitoring
Language
ISSN
1758-2652
Abstract
The HAART reduces the risk of HIV-related renal disease but the incidence of end-stage renal disease (ESRD). Therefore, efficacy and safety of renal transplantation (Tx) is an important resource in the HIV-infected population. We reported the results of kidney Tx in HIV+patients from deceased donors from June 2007 to March 2012 at our institution. The patients had to have CD4+T-cell counts≥200/mm3 and undetectable plasma HIV-RNA if on HAART. The induction immunosuppressive therapy consisted of metilprednisolone and basilixmab; tacrolimus and/or mycofenolic acid were used for maintenance therapy. The therapeutic drug monitoring (TDM) has been performed for the adjusting of both their doses []. A total of 14 patients underwent kidney Tx. They were on dialysis (haemodialysis=13, 92.9%; peritoneal=1, 7.1%) for 5±3.1 years and they were included on the Tx waiting list for 10±8 months. The baseline characteristics are showed in Table 1. [ABSTRACT FROM AUTHOR]