학술논문

Intracellular Anions as the Voltage Sensor of Prestin, the Outer Hair Cell Motor Protein.
Document Type
Article
Source
Science. 6/22/2001, Vol. 292 Issue 5525, p2340-2343. 4p. 5 Graphs.
Subject
*MEMBRANE proteins
*HAIR cells
*CELL motility
*COCHLEA
*CYTOLOGY
Language
ISSN
0036-8075
Abstract
Studies the contribution of the membrane protein prestin to the electromotility of the outer hair cells (OHC) of the mammalian cochlea. Characterization of the prestin molecule; Possibility that the voltage sensor may be a charged particle extrinsic to the protein; Elimination of voltage-dependent motility of OHC after removal of chloride.