학술논문
Tracking Emergence and Spread of SARS-CoV-2 Omicron Variant in Large and Small Communities by Wastewater Monitoring in Alberta, Canada.
Document Type
Article
Author
Hubert, Casey R.J.; Acosta, Nicole; Waddell, Barbara J. M.; Hasing, Maria E.; Yuanyuan Qiu; Fuzzen, Meghan; Harper, Nathanael B. J.; Bautista, María A.; Tiejun Gao; Chloe Papparis; Jenn Van Doorn; Kristine Du; Kevin Xiang; Leslie Chan; Vivas, Laura; Pradhan, Puja; McCalder, Janine; Low, Kashtin; England, Whitney E.; Kuzma, Darina
Source
Subject
Language
ISSN
1080-6040
Abstract
Wastewater monitoring of SARS-CoV-2 enables early detection and monitoring of the COVID-19 disease burden in communities and can track specific variants of concern. We determined proportions of the Omicron and Delta variants across 30 municipalities covering >75% of the province of Alberta (population 4.5 million), Canada, during November 2021-January 2022. Larger cities Calgary and Edmonton exhibited more rapid emergence of Omicron than did smaller and more remote municipalities. Notable exceptions were Banff, a small international resort town, and Fort McMurray, a medium-sized northern community that has many workers who fly in and out regularly. The integrated wastewater signal revealed that the Omicron variant represented close to 100% of SARS-CoV-2 burden by late December, before the peak in newly diagnosed clinical cases throughout Alberta in mid-January. These findings demonstrate that wastewater monitoring offers early and reliable population-level results for establishing the extent and spread of SARS-CoV-2 variants. [ABSTRACT FROM AUTHOR]