학술논문

The R131 low-affinity allele of the Fc gamma RIIA receptor is associated with systemic lupus erythematosus but not with other autoimmune diseases in French Caucasians.
Document Type
Journal Article
Source
American Journal of Medicine. May2000, Vol. 108 Issue 7, p580-583. 4p. 1 Black and White Photograph, 2 Charts.
Subject
*GENETICS of autoimmune diseases
*SYSTEMIC lupus erythematosus
*GENETICS
*ALLELES
*ANTIGENS
*ANTIPHOSPHOLIPID syndrome
*CELL receptors
*LUPUS erythematosus
*MULTIPLE sclerosis
*THYROIDITIS
*WHITE people
*CASE-control method
*GENOTYPES
Language
ISSN
0002-9343
Abstract
Compares the distribution of the R131/H131 isoforms in patients of French Caucasian origin who had autoimmune disorders. Difference in the distribution of the three genotypes when patients with systemic lupus erythematosus (SLE) were compared with healthy controls; Association of the R131 FcgammaRIIA allele with SLE in French Caucasian patients.