학술논문

Recent progress in the development of ursolic acid derivatives as anti‐diabetes and anti‐cardiovascular agents.
Document Type
Article
Source
Chemical Biology & Drug Design. Dec2023, Vol. 102 Issue 6, p1643-1657. 15p.
Subject
*URSOLIC acid
*ACID derivatives
*HYPOGLYCEMIC agents
*BIOAVAILABILITY
Language
ISSN
1747-0277
Abstract
Ursolic acid (UA) is a pentacyclic triterpenoid, which exhibits many biological activities, particularly in anti‐cardiovascular and anti‐diabetes. The further application of UA is greatly limited due to its low bioavailability and poor water solubility. Up to date, various UA derivatives have been designed to overcome these shortcomings. In this paper, the authors reviewed the development of UA derivatives as the anti‐diabetes anti‐cardiovascular reagents. [ABSTRACT FROM AUTHOR]