학술논문

B-cell reconstitution recapitulates B-cell lymphopoiesis following haploidentical BM transplantation and post-transplant CY.
Document Type
Article
Source
Bone Marrow Transplantation. Feb2015, Vol. 50 Issue 2, p317-319. 3p. 2 Graphs.
Subject
*B cells
*LYMPHOMA treatment
*CYCLOPHOSPHAMIDE
*BONE marrow transplantation
*CELL differentiation
*TRANSPLANTATION of organs, tissues, etc.
Language
ISSN
0268-3369
Abstract
The article discusses research which examines the effectiveness of B-cell reconstitution for the treatment of B-cell lymphopoiesis following haploidentical bone marrow transplantation and post-transplant cyclophosphamide (Cy). It shows that B-cell compartment was progressively repopulated by mature naive B cells. It reveals the dependence of B-cell recovery on a maturation process originating from donor B-cell precursors.