학술논문
The factor V Leiden mutation (R506Q) is not a major risk factor for migrainous cerebral infarction.
Document Type
Journal Article
Author
Source
Subject
*CLUSTER headache
*CEREBRAL infarction
*PROTEIN C
*MIGRAINE
*BLOOD coagulation factors
*BLOOD proteins
*INFARCTION
*GENETIC mutation
MIGRAINE complications
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Language
ISSN
0333-1024
Abstract
The etiology of migrainous cerebral infarction is unknown, but may involve prothrombotic coagulation abnormalities. Therefore, we studied resistance to activated protein C and the presence of the Arg506Gln factor V Leiden mutation in 20 patients with migrainous cerebral infarction. Only one heterozygous carrier of the mutation was found, whereas other patients did not carry the mutation. This indicates that the factor V Leiden mutation is not a major risk factor for migrainous cerebral infarction. [ABSTRACT FROM AUTHOR]