학술논문
Cancer-associated fibroblast-derived gene signatures determine prognosis in colon cancer patients.
Document Type
Letter
Author
Source
Subject
*COLON cancer prognosis
*CANCER patients
*GENES
*RECTAL cancer
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Language
ISSN
1476-4598
Abstract
CAF-related signatures showed stronger poor prognosis association in those patients with advanced colon tumors than in initial stages and in those patients with CMS4 than in CMS1-3. Patient classification is based on tumor microenvironment differences defined by CAF-derived signatures, in order to identify those patients with high/low risk of poor outcome. Keywords: Colon Cancer; Tumor microenvironment; Cancer-associated fibroblasts; Exosomes; Noncoding RNAs; Prognostic signatures; Liquid biopsy EN Colon Cancer Tumor microenvironment Cancer-associated fibroblasts Exosomes Noncoding RNAs Prognostic signatures Liquid biopsy 1 6 6 05/03/21 20210429 NES 210429 Mercedes Herrera, Alberto Berral-González, Cristina Peña, Vanesa García-Barberán and Javier De Las Rivas contributed equally to this work. [Extracted from the article]