부산대학교 도서관

This article discusses a case report of a rare condition called lymphocyte-variant hypereosinophilic syndrome (L-HES) that mimicked IgG4-related lymphadenopathy. L-HES is characterized by abnormal T-cell populations and excessive Th2 cytokine production, leading to hypereosinophilia. The patient in this case had generalized lymphadenopathy and high levels of IgG4-positive plasma cells in the lymph nodes, which initially suggested IgG4-related lymphadenopathy. However, further examination revealed the presence of aberrant T-cell populations, leading to the diagnosis of L-HES. This case highlights the importance of careful clinical and pathological review to differentiate between these two conditions. [Extracted from the article]