학술논문

Disseminated Bisifusarium infection following toxic epidermal necrolysis in a child with B-cell acute lymphoblastic leukemia.
Document Type
Article
Source
Pediatric Dermatology. May/Jun2023, Vol. 40 Issue 3, p503-506. 4p.
Subject
*LYMPHOBLASTIC leukemia
*TOXIC epidermal necrolysis
*ACUTE leukemia
*ANTIFUNGAL agents
*OPPORTUNISTIC infections
*INFECTION
*CANDIDA
Language
ISSN
0736-8046
Abstract
Fusarium is a polyphyletic genus of plant pathogens, members of which can cause opportunistic human infections with varying superficial and systemic presentations, including disseminated infections which typically occur in immunocompromised patients and have a poor prognosis. Treatment is challenging due to intrinsic resistance to many antifungal agents, and antifungal susceptibility testing is therefore essential. Early suspicion, isolation of the organism, and prompt initiation of management are crucial to improving survival. We present a case of disseminated Bisifusarium infection following toxic epidermal necrolysis in a child with B-cell acute lymphoblastic leukemia, successfully treated with liposomal amphotericin B, voriconazole, flucytosine, and terbinafine. [ABSTRACT FROM AUTHOR]