부산대학교 도서관

Objectives: The aim of this longitudinal study was to examine the distribution of head and neck cancer (HANC) disease burden across the region comparing it to national trends. Design: We undertook a retrospective study of routine data combining it with indicators of deprivation and lifestyle at small geographical areas within the 9 Local Authorities (LAs) of Merseyside and Cheshire Network (MCCN) for head and neck cancers. Data from the North West of England and England were used as comparator regions. Setting: This research was undertaken by the Cheshire and Merseyside Public Health Collaborative, UK. Participants: The Merseyside and Cheshire region serves a population of 2.2 million. Routine data allowed us to identify HANC patients diagnosed with cancers coded ICD C00‐C14 and C30‐C32 within 3 cohorts 1998‐2000, 2008‐2010 and 2009‐2011 for our analysis. Main Outcome Measures: Directly age‐standardised incidence rates and directly age‐standardised mortality rates in the LAs and comparator regions were measured. Lifestyle and deprivation indicators were plotted against them and measured by Pearson's correlation coefficients. Results: The incidence of head and neck cancer has increased across the region from 1998‐2000 to 2008‐2010 with a peak incidence for Liverpool males at 35/100 000 population. Certain Middle Super Output Areas contribute disproportionately to the significant effect of incidence and mortality within LAs. Income deprivation had the strongest correlation with incidence (r = .59) and mortality (r = .53) of head and neck cancer. Conclusion: Our study emphasises notable geographical variations within the region which need to be addressed through public health measures. [ABSTRACT FROM AUTHOR]