학술논문
Nontuberculous Mycobacterial Infections in Pediatric Solid Organ Transplant and Hematopoietic Cell Transplant Recipients.
Document Type
Article
Source
Subject
*MYCOBACTERIAL disease treatment
*MYCOBACTERIAL disease diagnosis
*HEMATOPOIETIC stem cell transplantation
*MYCOBACTERIAL diseases
*ANTIBIOTICS
*TRANSPLANTATION of organs, tissues, etc.
*PATIENTS
*MICROBIAL sensitivity tests
*DRUG resistance in microorganisms
*TREATMENT duration
*DRUG interactions
*DISEASE risk factors
*CHILDREN
*SYMPTOMS
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Language
ISSN
2048-7193
Abstract
The diagnosis of nontuberculous mycobacterial infections is challenging in pediatric solid organ transplant and hematopoietic cell transplant recipients due to the absence of specific clinical manifestations, limitations of sampling, prolonged times for culture and identification, and difficulty discerning colonization from clinical disease. Treatment is dependent on the nontuberculous mycobacterial species, disease type, and pattern of drug resistance. Treatment of nontuberculous mycobacterial infections involves prolonged durations of therapy using multiple medications, which are limited by toxicities and drug–drug interactions. [ABSTRACT FROM AUTHOR]