학술논문
Breakthrough Invasive Fungal Infection After Coadministration of Venetoclax and Voriconazole.
Document Type
Article
Author
Source
Subject
Language
ISSN
2328-8957
Abstract
Venetoclax requires a 75% dose reduction when coadministered with voriconazole. In a 10-year historical cohort of treatment with venetoclax, we did not observe a worse hematologic outcome in patients who received voriconazole prophylaxis versus those who did not. Subtherapeutic voriconazole levels and a triazole exposure history may contribute to breakthrough invasive fungal infection. [ABSTRACT FROM AUTHOR]