학술논문

Investigation of Hepatitis B, Hepatitis C, and Human Immunodeficiency Virus Seroprevalence in Pregnant Patients Admitted to a Secondary Level Hospital.
Document Type
Article
Source
Archives of Basic & Clinical Research. Sep2023, Vol. 5 Issue 3, p320-324. 5p.
Subject
*HEPATITIS B vaccines
*SEROPREVALENCE
*VIRAL hepatitis
*MATERNAL health
*ENZYME-linked immunosorbent assay
Language
ISSN
2687-4482
Abstract
Objective: In this study, it was aimed to analyze viral hepatitis and human immunodeficiency virus serology of pregnant patients admitted to Cizre State Hospital. Methods: Patients admitted to Cizre State Hospital Obstetrics and Gynecology Polyclinic between January 2017 and May 2022 due to pregnancy were included in the study. Hepatitis B surface antigen, hepatitis B surface antibody, hepatitis C virus antibody, human immunodeficiency virus antibody, and anti-HBc IgG values of the pregnant women studied by enzyme-linked immunosorbent assay method were examined. Results: In the study, 24.22% of pregnant women were examined in terms of viral hepatitis and human immunodeficiency virus disease. The mean age of 4548 pregnant women included in the study was 29 ± 6.07 years. Serologically, hepatitis B surface antigen (93.99%) was the most requested test. Hepatitis B surface antigen positivity was detected in 45 pregnant women (1.05%), and 25 of them (55.55%) did not apply to the Infectious Diseases and Clinical Microbiology outpatient clinic for further examination and treatment. Eighty percent of patients with hepatitis B surface antigen positivity were hepatitis B e antigen-negative chronic hepatitis B virus infection. Hepatitis B surface antibody positivity was 35.68%. Hepatitis B surface antibody positivity was present in 33.79% of pregnant women who were born before 1998, when the routine hepatitis B vaccination program began, and in 47.78% of pregnant women born after 1998. As high as 0.41% of pregnant women were hepatitis C virus antibody positive. All of the 21 pregnant women whose first human immunodeficiency virus antibody tests were positive (0.64%) had negative control human immunodeficiency virus antibody results. Conclusion: In this study, the low rate (24.22%) of pregnant women were examined in terms of viral hepatitis and HIV disease indicating that more importance should be given to viral hepatitis screening. Hepatitis B surface antigen positivity was detected in 1.05% of pregnant women. It was a positive data that the anti-HBs test was found to be positive at a higher rate (47.78%) in pregnant women born after the routine hepatitis B vaccination was started in our country. [ABSTRACT FROM AUTHOR]