부산대학교 도서관

COVID-19, sleep, ARDS, circadian health, critical care medicine, respiratory neurobiology, sleep disorders In non-COVID-19-related ARDS survivors, short-term poor sleep quality is also reported and the circadian rest-activity pattern is remarkably unstable, fragmented and less robust compared to community-dwelling adults.5,6 To our knowledge, this is the first study presenting a proper characterization of sleep and circadian health of COVID-19 patients in the long term, which is also relevant to long-term evaluations of ARDS patients. Keywords: ARDS; circadian health; COVID-19; critical care medicine; respiratory neurobiology; sleep; sleep disorders EN ARDS circadian health COVID-19 critical care medicine respiratory neurobiology sleep sleep disorders 1083 1088 6 11/21/22 20221201 NES 221201 Coronavirus disease 2019 (COVID-19) and the development of acute respiratory distress syndrome (ARDS) are often related to hospitalization and/or intensive care unit (ICU) admission, a context that leads to several sequelae.1 We evaluated 172 critical COVID-19 survivors and observed that 60.5% presented with poor sleep quality 3 months after hospital discharge, with a remarkable fragmentation of the circadian rest-activity pattern, which was predicted by the use of invasive mechanical ventilation (IMV) during ICU stay.2 Nevertheless, long-term evaluations of sleep within this context are scarce and mainly based on self-reported symptom questionnaires, while the assessment of circadian function is yet to be performed.3 Hence, we aimed to investigate the sleep and circadian health of critical COVID-19 survivors 6 months after hospital discharge. In summary, our findings reveal that sleep and circadian alterations are maintained in COVID-19 survivors who developed ARDS and were admitted to the ICU. [Extracted from the article]