학술논문
'학술논문'
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1~20
Report
A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma
Report
A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP -deletion (Master Protocol)
Report
A Phase 1/1b/2 Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 193 Alone and in Combination With Docetaxel in Subjects With Advanced MTAP -null Solid Tumors
Report
A First-in-human Study to Evaluate the Safety, Tolerability and Pharmacokinetics, Pharmacodynamics and Preliminary Clinical Activity of BAY 3713372, a Novel 2nd Generation PRMT5 Inhibitor, in Participants With MTAP -deleted Solid Tumors.
Report
A Phase 1a/1b Study Evaluating the Clinical Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Efficacy of PEP08 as Monotherapy and Combination Therapy in MTAP -Del Advanced or Metastatic Solid Tumors
Report
A Multi-center, Open-label, Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of CTS3497 in Patients With MTAP Deficient Advanced Solid Tumors and Lymphomas
Report
PRIMROSE: A Modular Phase I/IIa, Multi-centre, Dose Escalation, and Expansion Study of AZD3470, a MTA Cooperative PRMT5 Inhibitor, as Monotherapy and in Combination With Anticancer Agents in Patients With Advanced/Metastatic Solid Tumors That Are MTAP Deficient
Report
A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG462 as a Single Agent and in Combination in Patients With MTAP -deleted Advanced or Metastatic Solid Tumors
Report
A Phase 1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 193 in Combination With Other Therapies in Subjects With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous MTAP -deletion
Report
A Phase 1/2, Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Antitumor Activity of TNG456 Monotherapy and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss
Report
A Phase 1/2, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG908 in Patients With MTAP -deleted Advanced or Metastatic Solid Tumors
Academic Journal
In ESMO Open April 2025 10(4)
Report
A Multicenter, Randomized, Open-label, Phase 2 Study Evaluating the Safety and Efficacy of BMS-986504 Monotherapy in Participants With Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) With Homozygous MTAP Deletion After Progression on Prior Therapies
Report
A Phase I, Open-label, Dose-escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic of HSK41959 in Patients With MTAP Deletion Locally Advanced or Metastatic Solid Tumors
Report
A Phase 1 Multiple Expansion Cohort Trial of MRTX1719 in Patients With Advanced Solid Tumors With Homozygous MTAP Deletion
Academic Journal
Gorbokon, Natalia; Teljuk, Katharina; Reiswich, Viktor; Lennartz, Maximilian; Minner, Sarah; Simon, Ronald; Sauter, Guido; Wilczak, Waldemar; Clauditz, Till Sebastian; Schraps, Nina; Hackert, Thilo; Uzunoglu, Faik G.; Kluth, Martina; Bubendorf, Lukas; Matter, Matthias; Viehweger, Florian; Freytag, Morton; Jacobsen, Frank; Möller, Katharina; Steurer, Stefan
eBook
Computational Biology of Transcription Factor Binding. 08/23/2010. 674:121-141
Academic Journal
Gorbokon, Natalia ; Büyücek, Seyma ; Plage, Henning ; Heckmann, Neele ; Simon, Ronald ; Lennartz, Maximilian ; Kluth, Martina ; Teljuk, Katharina ; Hube-Magg, Claudia ; Minner, Sarah ; Burandt, Eike ; Clauditz, Till S. ; Wilczak, Waldemar ; Sauter, Guido ; Dum, David ; Hinsch, Andrea ; Heinzer, Hans ; Haese, Alexander ; Schlomm, Thorsten ; Luebke, Andreas M ; Graefen, Markus ; Steurer, Stefan ; Bernreuther, Christian ; Roma, Luca ; Bubendorf, Lukas ; Weinberger, Sarah
In Neoplasia September 2025 67
Report
A Phase 2 Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of AMG 193 in Subjects With Methylthioadenosine Phosphorylase (MTAP )-Deleted Previously Treated Advanced Non-Small Cell Lung Cancer (NSCLC)
Academic Journal
Mu, Haoran ; Zhang, Qi ; Zuo, Dongqing ; Wang, Jinzeng ; Tao, Yining ; Li, Zhen ; He, Xin ; Meng, Huanliang ; Wang, Hongsheng ; Shen, Jiakang ; Sun, Mengxiong ; Jiang, Yafei ; Zhao, Weisong ; Han, Jing ; Yang, Mengkai ; Wang, Zhuoying ; Lv, Yu ; Yang, Yuqin ; Xu, Jing ; Zhang, Tao ; Yang, Liu ; Lin, Jun ; Tang, Feng ; Tang, Renhong ; Hu, Haiyan ; Cai, Zhengdong ; Sun, Wei ; Hua, Yingqi
In Cell Reports Medicine 18 March 2025 6(3)
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