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Nature medicine. 27(4):546

Baryawno, N; Przybylski, D; Kowalczyk, MS; Kfoury, Y; Severe, N; Gustafsson, K; Kokkaliaris, KD; Mercier, F; Tabaka, M; Hofree, M; Dionne, D; Papazian, A; Lee, D; Ashenberg, O; Subramanian, A; Vaishnav, ED; Rozenblatt-Rosen, O; Regev, A; Scadden, DT

Cell. 177(7):1915

Zhivaki D; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Kennedy SN; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Park J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Boriello F; Harvard Medical School and Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Devant P; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Cao A; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Bahleda KM; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Murphy S; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McCabe C; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Evavold CL; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Chapman KL; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA.; Zanoni I; Harvard Medical School and Division of Immunology, Boston Children's Hospital, Boston, MA, USA.; Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Xavier RJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kagan JC; Harvard Medical School and Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA. Electronic address: jonathan.kagan@childrens.harvard.edu.

Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Ding J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Computer Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.; Garber JJ; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA. garber.md@gmail.com.; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA. garber.md@gmail.com.; Uchida A; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Lefkovith A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Carter GT; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Vimalathas P; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.; Canha L; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Dougan M; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Staller K; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Yarze J; Gastrointestinal Division, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.; Delorey TM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Genentech, South San Francisco, CA, 94080, USA.; Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Graham DB; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.; Deguine J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. aviv.regev.sc@gmail.com.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA. aviv.regev.sc@gmail.com.; Genentech, South San Francisco, CA, 94080, USA. aviv.regev.sc@gmail.com.; Xavier RJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. xavier@molbio.mgh.harvard.edu.; Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA. xavier@molbio.mgh.harvard.edu.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA. xavier@molbio.mgh.harvard.edu.; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA. xavier@molbio.mgh.harvard.edu.

Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Zhao W; Kepecs B; Mahadevan NR; Segerstolpe A; Weirather JL; Besson NR; Giotti B; Soong BY; Li C; Vigneau S; Slyper M; Wakiro I; Jane-Valbuena J; Ashenberg O; Rotem A; Bueno R; Rozenblatt-Rosen O; Pfaff K; Rodig S; Hata AN; Regev A; Johnson BE; Tsankov AM

Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Patel AG; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; These authors contributed equally.; Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; These authors contributed equally.; Collins NB; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.; These authors contributed equally.; Segerstolpe Å; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Jiang S; Department of Pathology, Stanford University, Stanford, CA, USA.; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Slyper M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Huang X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Caraccio C; Department of Pathology, Stanford University, Stanford, CA, USA.; Jin H; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.; Sheppard H; Comparative Pathology Core, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Xu K; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.; Chang TC; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.; Orr BA; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Shirinifard A; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Chapple RH; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Shen A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Clay MR; Department of Pathology, University of Colorado School of Medicine, Aurora, CO, USA.; Tatevossian RG; Cancer Biomarkers Laboratory, St. Jude Children's Research Hospital, Memphis, TN, USA.; Reilly C; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Patel J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Lupo M; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Cline C; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Dionne D; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Porter CBM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Waldman J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bai Y; Department of Pathology, Stanford University, Stanford, CA, USA.; Zhu B; Department of Pathology, Stanford University, Stanford, CA, USA.; Barrera I; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Murray E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Vigneau S; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Napolitano S; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Wakiro I; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Wu J; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Grimaldi G; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Dellostritto L; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Helvie K; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Rotem A; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Lako A; Center for Immuno-Oncology (CIO), Dana-Farber Cancer Institute, Boston, MA, USA.; Cullen N; Center for Immuno-Oncology (CIO), Dana-Farber Cancer Institute, Boston, MA, USA.; Pfaff KL; Center for Immuno-Oncology (CIO), Dana-Farber Cancer Institute, Boston, MA, USA.; Karlström Å; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Jané-Valbuena J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Todres E; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Thorner A; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Geeleher P; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.; Zhou X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Stewart E; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Johnson BE; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Wu G; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Chen F; Broad Institute of MIT and Harvard, Boston, MA, USA.; Yu J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Goltsev Y; Department of Pathology, Stanford University, Stanford, CA, USA.; Nolan GP; Department of Pathology, Stanford University, Stanford, CA, USA.; Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Current address: Research and Early Development, Genentech Inc., South San Francisco, CA, 94080, USA.; Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; Koch Institute of Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Current address: Research and Early Development, Genentech Inc., South San Francisco, CA, 94080, USA.; Lead contacts.; Dyer MA; Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA.; Lead contacts.

Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Bod L; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Massachusetts General Hospital Cancer Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Kye YC; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Shi J; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; BeiGene, Beijing, China.; Torlai Triglia E; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Schnell A; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Fessler J; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Division of Immunology and Pathophysiology, Medical University of Graz, Graz, Austria.; Ostrowski SM; Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA.; Von-Franque MY; Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA.; Kuchroo JR; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA.; Barilla RM; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Zaghouani S; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Christian E; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Delorey TM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Mohib K; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Xiao S; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Slingerland N; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Giuliano CJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Li Z; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Rothstein DM; Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Fisher DE; Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA.; Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Department of Biology and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Sharpe AH; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA.; Quintana FJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Department of Biology and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Apetoh L; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.; INSERM, Tours, France.; Faculté de Médecine, Université de Tours, Tours, France.; Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Howard Hughes Medical Institute, Department of Biology and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Genentech, San Francisco, CA, USA. aviv.regev.sc@gmail.com.; Kuchroo VK; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA. vkuchroo@rics.bwh.harvard.edu.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. vkuchroo@rics.bwh.harvard.edu.; Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. vkuchroo@rics.bwh.harvard.edu.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Kong L; Pokatayev V; Lefkovith A; Carter GT; Creasey EA; Krishna C; Subramanian S; Kochar B; Ashenberg O; Lau H; Ananthakrishnan AN; Graham DB; Deguine J; Xavier RJ

Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: PubMed not MEDLINE; MEDLINE

Emont MP; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Jacobs C; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Essene AL; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Pant D; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Tenen D; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Colleluori G; Department of Experimental and Clinical Medicine, Center of Obesity, Marche Polytechnic University, Ancona, Italy.; Di Vincenzo A; Department of Experimental and Clinical Medicine, Center of Obesity, Marche Polytechnic University, Ancona, Italy.; Jørgensen AM; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Dashti H; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stefek A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGonagle E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Strobel S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Laber S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Agrawal S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Westcott GP; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Kar A; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Veregge ML; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Gulko A; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Srinivasan H; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kramer Z; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; De Filippis E; Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic Scottsdale, AZ, USA.; Merkel E; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Ducie J; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Boyd CG; Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Gourash W; Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Courcoulas A; Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.; Lin SJ; Division of Plastic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Lee BT; Division of Plastic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Morris D; Division of Plastic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Tobias A; Division of Plastic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Khera AV; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Genomic Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Division of Plastic Surgery, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Claussnitzer M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Giordano A; Department of Experimental and Clinical Medicine, Center of Obesity, Marche Polytechnic University, Ancona, Italy.; Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Howard Hughes Medical Institute, Koch Institute of Integrative Cancer Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA.; Tsai LT; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Rosen ED; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center, Boston, MA, USA. erosen@bidmc.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. erosen@bidmc.harvard.edu.; Harvard Medical School, Boston, MA, USA. erosen@bidmc.harvard.edu.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: PubMed not MEDLINE; MEDLINE

Jardine, L; Webb, S; Goh, I; Londono, MQ; Reynolds, G; Mather, M; Olabi, B; Stephenson, E; Botting, RA; Horsfall, D; Engelbert, J; Maunder, D; Mende, N; Murnane, C; Dann, E; McGrath, J; King, H; Kucinski, I; Queen, R; Carey, CD; Shrubsole, C; Poyner, E; Acres, M; Jones, C; Ness, T; Coulthard, R; Elliott, N; O'Byrne, S; Haltalli, MLR; Lawrence, JE; Lisgo, S; Balogh, P; Meyer, KB; Prigmore, E; Ambridge, K; Jain, MS; Efremova, M; Pickard, K; Creasey, T; Bacardit, J; Henderson, D; Coxhead, J; Filby, A; Hussain, R; Dixon, D; McDonald, D; Popescu, D-M; Kowalczyk, MS; Li, B; Ashenberg, O; Tabaka, M; Dionne, D; Tickle, TL; Slyper, M; Rozenblatt-Rosen, O; Regev, A; Behjati, S; Laurenti, E; Wilson, NK; Roy, A; Goettgens, B; Roberts, I; Teichmann, SA; Haniffa, M