학술논문
IRG1/Itaconate inhibits hepatic stellate cells ferroptosis and attenuates TAA-induced liver fibrosis by regulating SLC39A14 expression
Document Type
Article
Author
Zhou, Pei ; Yang, Lei ; Li, Hang ; Zeng, Liwu ; Zhang, Yizhuo ; Zhong, Ziyou ; Li, Ruidong ; Yin, Yuping ; Tao, Kaixiong ; Zhang, Peng
Source
In International Immunopharmacology 27 January 2025 146
Subject
Language
ISSN
1567-5769
Abstract
Highlights •IRG1/Itaconate could attenuates TAA-induced hepatic fibrosis in mice.•IRG1/Itaconate inhibits hepatic stellate cells ferroptosis.•IRG1/Itaconate axis could target and regulate the expression of SLC39A14.