학술논문
Low-intensity ultrasound-assisted adaptive laboratory evolution of Bacillus velezensis for enhanced production of peptides
Document Type
Article
Author
Source
In Ultrasonics Sonochemistry February 2024 103
Subject
Language
ISSN
1350-4177
Abstract
This work aimed to explore low-intensity ultrasound-assisted adaptive laboratory evolution (US-ALE) of Bacillus velezensis and fermentation performance of mutant strains were investigated by nitrogen transformation metabolism. Results showed ultrasound accelerated the process of adaptive evolution and enhanced cell dry weight, amylase and protease activity of mutant strains, accompanied with the improved transformation abilities of NO–3-N to NH4+-N. Compared with original strain, the total peptide-N, peptide-N (