학술논문
Ultrasensitive electrochemical DNAzyme sensor for lead ion based on cleavage-induced template-independent polymerization and alkaline phosphatase amplification
Document Type
Article
Author
Source
In Biosensors and Bioelectronics 15 September 2016 83:33-38
Subject
Language
ISSN
0956-5663
Abstract
Highlights •A highly sensitive and selective electrochemical DNAzyme sensor for Pb2+ was developed.•The 8–17 DNAzyme cleavage-induced template-independent extension was utilized for amplification.•An impressive detection limit of 0.043nM toward Pb2+ could be achieved.•It opens a promising avenue for the detection of metal ions and other nucleic acid-related analytes.