학술논문

Xenon ventilation-perfusion lung scans. The early diagnosis of inhalation injury
Document Type
Journal Article
Author
Source
J. Am. Med. Assoc.; (United States); 240:22
Subject
62 RADIOLOGY AND NUCLEAR MEDICINE BURNS
DIAGNOSIS
LUNGS
SCINTISCANNING
RESPIRATORY SYSTEM DISEASES
XENON 133
INHALATION
INTRAVENOUS INJECTION
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
EVEN-ODD NUCLEI
INJECTION
INJURIES
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
XENON ISOTOPES 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
Language
English
Abstract
The use of xenon Xe-133 ventilation-perfusion lung scans for the early diagnosis of inhalation injury was evaluated in 67 patients with acute thermal burns. Study results were interpreted as normal if there was complete pulmonary clearance of the radioactive gas by 150 seconds. Thirty-two scans were normal, 32 abnormal, and three technically inadequate. There were three true false-positive study results and one false-negative study result. Good correlation was found between the scan results and various historical, physical, and laboratory values currently used to evaluate inhalation injury. The scans appeared to be the most sensitive method for the detection of early involvement, often being abnormal several days before the chest roentgenogram. Xenon lung scanning is a safe, easy, accurate, and sensitive method for the early diagnosis of inhalation injury and has important therapeutic and prognostic implications as well.