학술논문
Babesia divergens vaccine
Document Type
article
Author
Source
Memórias do Instituto Oswaldo Cruz. January 1992 87(3)
Subject
Language
English
ISSN
0074-0276
Abstract
A vaccine strategy against Babesia divergens bovine babesiosis was sucessfully developed after perfecting of an efficient in vitro culture. Crude supernatants and purified fractions were able to induce a vaccine protection in gerbils against B. divergens infection. More, supernatants induced an effective vaccine protection in cattle. The role of B. divergens exoantigens of 17, 37, 46, 70 and 90 kDa in the development of the immune response was cleary demonstrated in gerbils, cattle, and man.