학술논문

Choroidal Thickness in Multiple Sclerosis: An Optical Coherence Tomography Study
Document Type
article
Source
Journal of Clinical Neurology. 18(3)
Subject
Biomedical and Clinical Sciences
Ophthalmology and Optometry
Eye Disease and Disorders of Vision
Biomedical Imaging
Brain Disorders
Bioengineering
Autoimmune Disease
Neurodegenerative
Multiple Sclerosis
Clinical Research
Neurosciences
Detection
screening and diagnosis
4.2 Evaluation of markers and technologies
Neurological
choroidal thickness
optical coherence tomography
multiple sclerosis
optic neuritis
Clinical sciences
Biological psychology
Language
Abstract
Background and purposeTo identify changes in the choroidal thickness (CT) in multiple sclerosis (MS) patients with and without optic neuritis (ON) using enhanced-depth-imaging optical coherence tomography (EDI-OCT).MethodsThis cross-sectional study included 96 eyes with MS and 28 eyes of healthy controls. All participants underwent an ophthalmologic examination and EDI-OCT scanning (Spectralis, Heidelberg Engineering, Germany) to assess the CT and the retinal nerve fiber layer (RNFL) thickness. MS patients were divided into two groups: 1) with and 2) without a history of ON. The CT was evaluated in the fovea and at six horizontal and six vertical points at 500, 1,000, and 1,500 µm from the fovea. Paired t-tests were used to compare the groups, and p-value