학술논문

Toward an orthogonal central dogma
Document Type
article
Source
Nature Chemical Biology. 14(2)
Subject
Genetics
Underpinning research
1.1 Normal biological development and functioning
Biotechnology
DNA Replication
Genetic Engineering
Humans
Kluyveromyces
Macromolecular Substances
Mitochondria
Plasmids
Protein Biosynthesis
Ribosomes
Synthetic Biology
Transcription
Genetic
Medicinal and Biomolecular Chemistry
Biochemistry and Cell Biology
Biochemistry & Molecular Biology
Language
Abstract
The central dogma processes of DNA replication, transcription, and translation are responsible for the maintenance and expression of every gene in an organism. An orthogonal central dogma may insulate genetic programs from host regulation and allow expansion in the roles of these processes within the cell.