학술논문
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Document Type
redif-article
Author
Source
Nature, Nature. 530(7590):354-357
Subject
Language
English
Abstract
NEK7, a member of the NIMA-related kinase family, is identified as a regulator of NLRP3 inflammasome oligomerization and activation; NEK7 functions downstream of potassium efflux in a manner that is independent of its kinase activity.