학술논문
Topsentin compounds effective against viruses and certain tumors
Document Type
Patent
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Abstract
A new class of novel, biologically active bisindole alkaloid compounds, which have been named topsentins, pharmaceutical compositions containing them, methods of producing the compounds and methods of using them are disclosed. This new class of compounds has the generic formula: ##STR1## R.sup.1-8 are the same or different selected from --H, --OH, halogen, --R, --OR, --OCOR, or --OA;
Y is the single group --O, or two groups, same or different, selected from --H, --OH, --OR, or --OCOR with the provision that Y shall not be two --OH groups;
Z are the same or different selected from --H, --R;
R is C1-5 alkyl and A is --R--phenyl.
The compounds are antiviral agents and antitumor agents which are effective against specific tumors.
Y is the single group --O, or two groups, same or different, selected from --H, --OH, --OR, or --OCOR with the provision that Y shall not be two --OH groups;
Z are the same or different selected from --H, --R;
R is C1-5 alkyl and A is --R--phenyl.
The compounds are antiviral agents and antitumor agents which are effective against specific tumors.