부산대학교 도서관

Portal hypertensive bleeding encompasses a spectrum of conditions that include esophageal, gastric, and ectopic varices and portal hypertensive gastroenteropathy. Esophageal variceal hemorrhage occurs through a combination of increased portal pressure and local factors within the varix itself. Management of esophageal varices includes primary prophylaxis of variceal hemorrhage, treatment of actively bleeding varices, and prevention of variceal rebleeding (secondary prophylaxis). The choice of therapy for primary prophylaxis depends on patient preferences and includes pharmacologic therapy with nonselective β-blockers (NSBBs) or variceal band ligation, especially if NSBB therapy fails or is not tolerated by the patient. Active bleeding is best treated endoscopically.