학술논문
당뇨병 환자의 족부 진균 질환 유병률과 당뇨병성 족부 질환과의 상관성 조사
Prevalence of Fungal Infection on Foot in Diabetic Patients and Correlation between Diabetic Ulcer and Fungal Infection on Foot당뇨병 환자의 족부 진균 질환 유병률과 당뇨병성 족부 질환과의 상관성 조사
Prevalence of Fungal Infection on Foot in Diabetic Patients and Correlation between Diabetic Ulcer and Fungal Infection on Foot당뇨병 환자의 족부 진균 질환 유병률과 당뇨병성 족부 질환과의 상관성 조사
Document Type
Article
Author
이광훈 / Kwang Hoon Lee; 이주희 / Ju Hee Lee; 이정덕 / Jeong Deuk Lee; 조백기 / Baik Kee Cho; 김형옥 / Hyung Ok Kim; 김계정 / Kea Jeung Kim; 김낙인 / Nack In Kim; 송해준 / Hae Jun Song; 손숙자 / Sook Ja Son; 김상원 / Sang Won Kim; 박철종 / Chul Jong Park; 김기호 / Ki Ho Kim; 권경술 / Kyung Sool Kwon; 박욱화 / Wook Hwa Park; 이일수 / Eil Soo Lee; 변대규 / Dae Gyoo Byun; 김진우 / Jin Wou Kim; 김시용 / Si Yong Kim; 이종석 / Jong Suk Lee; 강원형 / Won Hyoung Kang; 박석돈 / Seok Don Park; 최응호 / Eung Ho Choi; 이애영 / Ai Young Lee; 이준영 / Jun Young Lee; 함정희 / Jeong Hee Hahm; 박성욱 / Sung Wook Park; 최광성 / Gwang Seong Choi; 원영호 / Young Ho Won; 서성준 / Seong Jun Seo; 노병인 / Byung In Ro; 김광중 / Kwang Joong Kim; 김종민 / Jong Min Kim; 유희준 / Hee Joon Yu
Source
대한피부과학회지 / Korean Journal of Dermatology. Jul 20, 2003 41(7):908
Subject
Language
Korean
ISSN
0494-4739
Abstract
Object : The purpose of this study was to determine the prevalence of fungal infection and ulcer on the feet of diabetic patients and the existence of correlation between ulcer and fungal infection. Methods : A total 21,693 outpatients diagnosed as diabetes mellitus at the department of endocrinology of 32 hospitals were examined. The diabetic patients with foot problems were consulted to the department of dermatology. Physical examination and KOH preparation were performed. Results : 13,271 patients had certain kinds of foot problem, accounting for 61.2% of 21,693 diabetics examined. Of these, fungal foot disease were found in 10,403 that constituted 78.4% (48.0% of the entire diabetic population). Tinea pedis was the diagnosis in 6,496 (29.9%), onychomycosis in 7,783 (35.9%), and coexistence was in 3,883 (17.9%). Foot deformity was in 1,346 (6.2% of diabetics; 10.1% of foot disease), non-palpable pulse in 1,051 (4.8% ; 7.9%), and foot ulcer was in 425 (2.0% ; 3.2%), following in a descending order of frequency. Odds ratios for diabetic foot ulcer were 2.5 in patients with the foot deformity, 1.6 with fungal foot disease and 2.2 with non-palpable pulse. Conversely, Odds ratios for fungal foot disease were 2.5 with foot deformity, and 1.6 with foot ulcer. A total of 5,486 patients paid a visit to the department of dermatology. Of these, 4,519 patients were diagnosed with fungal infection through physical examination and KOH smear by dermatologists. The population comprised of 2,272 males and 2,247 females, showing similar prevalence between sexes. However, age did have positive correlation regarding prevalence of fungal foot disease. The number of diabetic patients with toenail problems was 3,847 patients (70%) and onychomycosis was proven mycologically in 3,276. Onychomycosis of distal subungal type was the most common clinical finding, most frequently involving the great toenails. Abnormal skin findings of the foot were seen in 3,885(70.8%) and tinea pedis was found in 3,209 (58.5%), most commonly involving the soles. Conclusion : This study showed that fungal infection might be regarded as a risk factor of foot ulcer. Treatment of fungal infection in diabetic patients might prevent diabetic foot disease such as ulcer and reduce the disability, morbidity and mortality in diabetic patients. (Korean J Dermatol 2003;41(7) : 908~915)