부산대학교 도서관

Hobnail hemangiomas are benign vascular lesions, and their occurrence in the oral cavity is relatively rare. Here, we report a case of hobnail hemangioma that occurred on the tongue. The patient, an 84-year-old woman, was referred to our oral and maxillofacial surgery by the internal medicine department in June 2018. The mass on the lower surface of the right side of her tongue was a 6 × 6-mm-sized dark-brown, elastic, relatively hard, and elevated lesion that did not fade when pressure was applied. Total resection was performed under local anesthesia. Histopathological examination revealed a biphasic growth pattern with irregular, dilated, thin-walled vessels in the superficial parts of the lesion and slit-like vessels in the deeper portion. The plump endothelial cells in the superficial vessels showed the characteristic“ hobnail” appearance. Immunohistochemically, the endothelial cells were positive for endothelial markers and/or lymphatic endothelial markers to varying degrees. Based on the clinical and histopathological findings, the lesion was diagnosed as hobnail hemangioma. However, recurrence occurred 6 months after resection, so the mass and surrounding tissue were totally resected. The patient’s prognosis is currently favorable, with no signs of recurrence two years after the second resection.