학술논문
The Simplified Thrombo-inflammatory Score as a Novel Predictor of All-Cause Mortality in Patients with Heart Failure: A Retrospective Cohort Study
Document Type
Clinical report
Author
Source
Journal of Inflammation Research. March 31, 2024, Vol. 17, p1845, 11 p.
Subject
Language
English
ISSN
1178-7031
Abstract
Background: The simplified thrombo-inflammatory score (sTIPS) has recently emerged as a novel prognostic score. Hence, we investigated the prognostic value of sTIPS for predicting long-term mortality in patients with heart failure (HF). Methods: A total of 3741 patients were analyzed in this study. The sTIPS was calculated based on the white blood cell count (WBC) and the mean platelet volume to platelet count (MPV/PC) ratio at admission. The mean follow-up time was 22.75 months. Multivariable Cox regression analyses were used to investigate the associations between the sTIPS and all-cause mortality (ACM). Results: In the whole study population, multivariate Cox regression analysis showed that patients in both the sTIPS 2 and sTIPS 1 groups had significantly increased risk of ACM as compared with patients in the sTIPS 0 group (hazard ratio [HR]=1.706, 95% confidence interval [CI]: 1.405-2.072, P Conclusion: sTIPS is useful in predicting risk for long-term mortality in patients with HF. Keywords: simplified thrombo-inflammatory score, heart failure, prognosis, all-cause mortality
Introduction HF is a progressive clinical syndrome caused by abnormal cardiac structure or function in which patients have typical symptoms such as breathlessness, ankle swelling, and fatigue, as well as [...]
Introduction HF is a progressive clinical syndrome caused by abnormal cardiac structure or function in which patients have typical symptoms such as breathlessness, ankle swelling, and fatigue, as well as [...]