학술논문

Catalytic properties of ADAM12 and its domain deletion mutants
Document Type
Academic Journal
Source
Biochemistry. Jan 15, 2008, Vol. 47 Issue 2, p537, 11 p.
Subject
Transferrin -- Research
Transferrin -- Chemical properties
Metalloproteins -- Research
Metalloproteins -- Physiological aspects
Biological sciences
Chemistry
Language
English
ISSN
0006-2960
Abstract
A novel activity of recombinant ADAM12-S, a variant of human metalloproteinase ADAM 12, and its domain deletion mutants on S-carboxymethylated transferrin is reported. The results of the study indicate unique enzymatic properties of ADAM12 among the members of the ADAM family of metalloproteinases.