학술논문

Prediction of adverse outcomes in children with sickle cell disease
Document Type
Academic Journal
Source
The New England Journal of Medicine. Jan 13, 2000, Vol. 342 Issue 2, p83, 7 p.
Subject
Sickle cell anemia in children -- Complications
Language
ISSN
0028-4793
Abstract
Three complications of sickle cell anemia may predict serious complications later in life if they occur in the first two years of life. Researchers followed 392 babies diagnosed with sickle cell anemia until they were 10 years old. Children who subsequently died or had a stroke, frequent pain of acute chest syndrome were more likely to have had pain and tenderness in the hands or feet, a hemoglobin level less than 7, and elevated white blood cell counts in the absence of infection. These signs and symptoms all occurred in the first two years of life.