학술논문

Factors Associated with 30-Day in-Hospital Mortality Among Patients Admitted with Severe Covid-19 in Mbarara Regional Referral Hospital
Document Type
Academic Journal
Source
Infection and Drug Resistance. December 31, 2022, Vol. 15, p7157, 7 p.
Subject
Uganda
Language
English
ISSN
1178-6973
Abstract
Background: COVID-19 has created a burden on the healthcare system globally. Severe COVID-19 is linked with high hospital mortality. Data regarding 30-day in-hospital mortality and its factors has not been explored in southwestern Uganda. Methods: We carried out a retrospective, single-center cohort study, and included all in-patients with laboratory- confirmed, radiological, or clinical severe COVID-19 admitted between April 2020 and September 2021 at Mbarara Regional Referral Hospital (MRRH). Demographic, laboratory, treatment, and clinical outcome data were extracted from patients' files. These data were described comparing survivors and non-survivors. We used logistic regression to explore the factors associated with 30-day inhospital mortality. Results: Of the 283 patients with severe COVID-19 admitted at MRRH COVID-19 unit, 58.1% were male. The mean age [+ or -] standard deviation (SD) was 61[+ or -]17.4 years; there were no differences in mean age between survivors and non-survivors (59 [+ or -] 17.2 versus 64.4 [+ or -]17.3, respectively, p=0.24) The median length of hospital stay was 7 (IQR 3-10) days (non-survivors had a shorter median length of stay 5 (IQR 2-9) days compared to the survivors; 8 (IQR 5-11) days, p Conclusion: We found a high 30-day in-hospital mortality among patients with severe forms of COVID-19. The identified factors could help clinicians to identify patients with poor prognosis at an early stage of admission. Keywords: severe, COVID-19, 30-day in hospital mortality
Introduction The year 2020 will always be remembered as the "COVID-19" (Coronavirus disease 2019) year. COVID-19 is a viral infectious disease caused by the severe acute respiratory syndrome coronavirus 2 [...]