부산대학교 도서관

To authenticate to the full-text of this article, please visit this link: http://dx.doi.org/10.1111/j.1751-0813.2009.00430.x Byline: D Jordan (a), JJ-C Chin (a), VA Fahy (b), MD Barton (c), MG Smith (d), DJ Trott (e) Keywords: antibiotics; antimicrobials; pigs; surveys Abstract: Objective To describe how various antimicrobials are used in commercial pig herds in Australia and for what disease conditions. Procedure Managers of large pig herds (> 200 sows) across Australia and their veterinarians participated in an internet-based survey in 2006. Questions were asked about herd management, the occurrence of bacterial diseases and the type and frequency of antimicrobial use. An antimicrobial usage index for each herd was derived as a summary of the risk of selection for antimicrobial resistance. Relationships between responses were explored with univariate and multivariate analysis. Results Responses were received for 197 herds estimated to represent at least 51% of all large pig herds in Australia. Most piggeries relied on drugs of low importance in human medicine (e.g. tetracyclines, penicillins and sulfonamides). For the two drugs of high importance in human medicine that can be legally prescribed to pigs in Australia, ceftiofur use was reported in 25% of herds and virginiamycin in none. Infections attributed to Lawsonia, Mycoplasma and Escherichia coli motivated the most use of antimicrobials. No useful association was found between management factors and the antimicrobial use index. Conclusion Most antimicrobial use in the Australian pig industry is based on drugs of low importance to public health. Enhanced control of E. coli infections without reliance on antimicrobials would further reduce the risk of selecting for antimicrobial resistance relevant to public health. The amount of variation in the usage index between herds suggests that antimicrobial use should be constantly reviewed on a herd by herd basis. Author Affiliation: (a)New South Wales Department of Primary Industries, 1243 Bruxner Highway, Wollongbar, New South Wales 2477, Australia;david.jordan@dpi.nsw.gov.au (b)Elizabeth MacArthur Agricultural Institute, NSW DPI, Camden, NSW, Australia (c)Pig Health and Research Unit, Victorian DPI, Epsom, Victoria, Australia (d)University of South Australia, School of Pharmacy and Medical Science, Adelaide, South Australia, Australia (e)Faculty of Natural Resources, Agriculture and Veterinary Science, University of Queensland, St Lucia, Queensland, Australia Article History: (Accepted for publication 23 November 2008) doi: 10.1111/j.1751-0813.2009.00430.x Article note: (*) Correspondence author.