학술논문
Implementation of Electrochemiluminescence Microanalysis in PCB Technology
Document Type
Conference
Author
Source
2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE. :2944-2947 Aug, 2007
Subject
Language
ISSN
1094-687X
1558-4615
1558-4615
Abstract
We present an instrumental development to implement electrochemiluminescence (ECL) microanalysis using printed circuit board (PCB) technology. PCB gold macro-(10 mm 2 ) and micro- (0.09 mm 2 ) electrodes and two ECL microfluidic devices are designed, fabricated and tested via luminol ECL detection. Potential modulation is performed between 0.7 and 0 V vs. Ag/AgCl for luminol oxidation, thus giving rise to on/off ECL responses in the presence of hydrogen peroxide. Synchronous detection is adopted to allow weak ECL signal recovery at a very low signal-to-noise ratio (SNR). The detection limit obtained with the two ECL microfluidic devices is 50 nM and 100 nM H 2 O 2 for macroelectrodes and microelectrodes, respectively.