학술논문

Characterization of an In-Beam PET Prototype for Proton Therapy With Different Target Compositions
Document Type
Periodical
Source
IEEE Transactions on Nuclear Science IEEE Trans. Nucl. Sci. Nuclear Science, IEEE Transactions on. 57(3):1563-1569 Jun, 2010
Subject
Nuclear Engineering
Bioengineering
Positron emission tomography
Prototypes
Protons
Medical treatment
Imaging phantoms
Dosimetry
Radioactive decay
Yttrium
Detectors
Particle beams
Dose monitoring
positron emission tomography
proton therapy
Language
ISSN
0018-9499
1558-1578
Abstract
At the University of Pisa, the DoPET (Dosimetry with a Positron Emission Tomograph) project has focused on the development and characterization of an ad hoc, scalable, dual-head PET prototype for in-beam treatment planning verification of the proton therapy. In this paper we report the first results obtained with our current prototype, consisting of two opposing lutetium yttrium orthosilicate (LYSO) detectors, each one covering an area of 4.5$\times $4.5 ${\rm cm}^{2}$. We measured the $\beta ^{+}$-activation induced by 62 MeV proton beams at Catana facility (LNS, Catania, Italy) in several plastic phantoms. Experiments were performed to evaluate the possibility to extract accurate phantom geometrical information from the reconstructed PET images.