학술논문
A Compartmentalized Approach to the Assembly of Physical Maps
Document Type
Conference
Source
2007 IEEE 7th International Symposium on BioInformatics and BioEngineering Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on. :218-225 Oct, 2007
Subject
Language
Abstract
We propose a novel compartmentalized method for the assembly of physical maps from fingerprinted clones. Our assembler exploits the presence of genetic markers at the global level to improve the accuracy of the assembly. Experimental results on the genome of rice and barley demonstrate that the compartmentalized assembler produces significantly more accurate maps, and that it can detect and isolate clones that induce chimeric contigs.