학술논문

Can C-Reactive Protein (CRP) Time Series Forecasting be Achieved via Deep Learning?
Document Type
article
Source
IEEE Access, Vol 7, Pp 59311-59320 (2019)
Subject
Biomedical engineering
forecasting
autoregressive modeling
ARIMA
machine learning
deep learning
Electrical engineering. Electronics. Nuclear engineering
TK1-9971
Language
English
ISSN
2169-3536
Abstract
C-reactive protein (CRP) is a biomarker of inflammation and is widely considered as an indicator of cancer prognosis, risk, and recurrence in clinical experiments. Investigating the properties and behaviors of CRP time series has recently emerged as an area of significant interest in informing clinical decision making. The area of cancer immunotherapy is a key application where CRP forecasting is critically needed. Therefore, predicting the future values of a CRP time series can provide useful information for clinical purposes. In this paper, we focus on CRP time series forecasting, comparing autoregressive integrated moving average (ARIMA) modeling with deep learning. The CRP data are obtained from 24 patients with melanoma. This paper using CRP data indicates that deep learning provides significantly reduced prediction error compared to ARIMA modeling.