학술논문
Large-scale genomic analyses reveal insights into pleiotropy across circulatory system diseases and nervous system disorders
Document Type
article
Author
Xinyuan Zhang; Anastasia M. Lucas; Yogasudha Veturi; Theodore G. Drivas; William P. Bone; Anurag Verma; Wendy K. Chung; David Crosslin; Joshua C. Denny; Scott Hebbring; Gail P. Jarvik; Iftikhar Kullo; Eric B. Larson; Laura J. Rasmussen-Torvik; Daniel J. Schaid; Jordan W. Smoller; Ian B. Stanaway; Wei-Qi Wei; Chunhua Weng; Marylyn D. Ritchie
Source
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Circulatory system diseases and nervous system disorders often co-occur in patients. Here the authors use eMERGE and UK BioBank data to identify genomic regions associated with both phenotypes, providing insight into the relationship between these conditions.