학술논문
Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents
Document Type
article
Author
Nina Koerber; Alina Priller; Sarah Yazici; Tanja Bauer; Cho-Chin Cheng; Hrvoje Mijočević; Hannah Wintersteller; Samuel Jeske; Emanuel Vogel; Martin Feuerherd; Kathrin Tinnefeld; Christof Winter; Jürgen Ruland; Markus Gerhard; Bernhard Haller; Catharina Christa; Otto Zelger; Hedwig Roggendorf; Martin Halle; Johanna Erber; Paul Lingor; Oliver Keppler; Dietmar Zehn; Ulrike Protzer; Percy A. Knolle
Source
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Waning immunity to SARS-CoV-2 is of concern. Here the authors follow spike- and nucleocapsid specific immunity in convalescent individuals for 9 months observing a decline in antibody levels but persisting T cell response. Vaccination approximately 11 months after infection boosts antibody and T cell immunity.