학술논문
Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
Document Type
article
Author
Sergio Serrano-Villar; Alba Talavera-Rodríguez; María José Gosalbes; Nadia Madrid; José A. Pérez-Molina; Ryan J. Elliott; Beatriz Navia; Val F. Lanza; Alejandro Vallejo; Majdi Osman; Fernando Dronda; Shrish Budree; Javier Zamora; Carolina Gutiérrez; Mónica Manzano; María Jesús Vivancos; Raquel Ron; Javier Martínez-Sanz; Sabina Herrera; Uxua Ansa; Andrés Moya; Santiago Moreno
Source
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
It is unknown whether capsulized fecal microbiota transplantation (FMT) can modify the microbiota of people with HIV. Here, the authors report the results of a pilot double-blind study, where 30 HIV-infected subjects on ART were randomized to either weekly oral FMT capsules or placebo for 8 weeks, and show that transplanted microbiota successfully engrafts and is able to attenuate HIV-associated dysbiosis.