학술논문
Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test
Document Type
article
Author
Juan Pablo Hinestrosa; Razelle Kurzrock; Jean M. Lewis; Nicholas J. Schork; Gregor Schroeder; Ashish M. Kamat; Andrew M. Lowy; Ramez N. Eskander; Orlando Perrera; David Searson; Kiarash Rastegar; Jake R. Hughes; Victor Ortiz; Iryna Clark; Heath I. Balcer; Larry Arakelyan; Robert Turner; Paul R. Billings; Mark J. Adler; Scott M. Lippman; Rajaram Krishnan
Source
Communications Medicine, Vol 2, Iss 1, Pp 1-9 (2022)
Subject
Language
English
ISSN
2730-664X
Abstract
Hinestrosa et al. describe the early-stage detection of cancer using biomarkers present in circulating extracellular vesicles purified via an alternating current electrokinetics platform. They show, in a case-control study, that 95.7% of pancreatic, 75.0% of ovarian and 43.8% of bladder stage I and II cancers can be detected.