학술논문

Supramolecular nanomedicines based on host–guest interactions of cyclodextrins
Document Type
article
Source
Exploration, Vol 3, Iss 4, Pp n/a-n/a (2023)
Subject
cyclodextrins
host–guest interactions
supramolecular nanomedicines
Biotechnology
TP248.13-248.65
Language
English
ISSN
2766-2098
2766-8509
Abstract
Abstract In the biomedical and pharmaceutical fields, cyclodextrin (CD) is undoubtedly one of the most frequently used macrocyclic compounds as the host molecule because it has good biocompatibility and can increase the solubility, bioavailability, and stability of hydrophobic drug guests. In this review, we generalized the unique properties of CDs, CD‐related supramolecular nanocarriers, supramolecular controlled release systems, and targeting systems based on CDs, and introduced the paradigms of these nanomedicines. In addition, we also discussed the prospects and challenges of CD‐based supramolecular nanomedicines to facilitate the development and clinical translation of these nanomedicines.